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Chapman, Arlene
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phone +1 (773) 795-1376
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Concept Alanine Transaminase
Concept Activities of Daily Living
Concept Fabry Disease
Concept Aged, 80 and over
Concept Aldosterone
Concept Australia
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Concept Biphenyl Compounds
Concept African Americans
Concept Blood Flow Velocity
Concept Amino Acid Sequence
Concept Administration, Oral
Concept Alcohol Drinking
Concept Aldehyde Oxidoreductases
Concept Calcium Phosphates
Concept Intracranial Aneurysm
Concept Analgesics
Concept Aorta
Concept Amino Acids, Branched-Chain
Concept Chromosomes, Human, Pair 11
Concept Chromosomes, Human, Pair 2
Concept Antihypertensive Agents
Concept Analysis of Variance
Concept Anthropometry
Concept Benzazepines
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Concept Atenolol
Concept Bayes Theorem
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Concept Calmodulin-Binding Proteins
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Concept Chlorthalidone
Concept Chromosomes, Human, Pair 12
Concept Combined Modality Therapy
Concept Blood Pressure Determination
Concept Caffeine
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Concept Circadian Rhythm
Concept Coronary Artery Disease
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Concept Cytochrome P-450 Enzyme System
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Concept Chromosomes, Human, Pair 17
Concept Clinical Protocols
Concept Finland
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Concept Image Interpretation, Computer-Assisted
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Concept Metoprolol
Concept Mice, Transgenic
Concept Organ Size
Concept Puerto Rico
Concept Middle Aged
Concept Iothalamic Acid
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Concept Nephritis, Hereditary
Concept Genetic Markers
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Concept Polycystic Kidney Diseases
Concept Kininogens
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Concept Hypoxia-Inducible Factor 1, alpha Subunit
Concept Angiotensin II Type 1 Receptor Blockers
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Concept Polycystic Kidney, Autosomal Dominant
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Concept TRPP Cation Channels
Concept Glucose Transporter Type 5
Concept Young Adult
Concept Patient Safety
Academic Article Health-related quality of life in patients with autosomal dominant polycystic kidney disease and CKD stages 1-4: a cross-sectional study.
Academic Article Cystic and inherited kidney diseases.
Academic Article Sonographic assessment of the severity and progression of autosomal dominant polycystic kidney disease: the Consortium of Renal Imaging Studies in Polycystic Kidney Disease (CRISP).
Academic Article Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials.
Academic Article Plasma renin activity predicts blood pressure responses to beta-blocker and thiazide diuretic as monotherapy and add-on therapy for hypertension.
Academic Article Blood pressure in early autosomal dominant polycystic kidney disease.
Academic Article Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.
Academic Article Hypertension in autosomal dominant polycystic kidney disease.
Academic Article Comprehensive molecular diagnostics in autosomal dominant polycystic kidney disease.
Academic Article Is diabetes mellitus-linked amino acid signature associated with ß-blocker-induced impaired fasting glucose?
Academic Article Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases.
Academic Article Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort.
Academic Article Renal relevant radiology: radiologic imaging in autosomal dominant polycystic kidney disease.
Academic Article Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.
Academic Article Tolvaptan in autosomal dominant polycystic kidney disease: three years' experience.
Academic Article Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.
Academic Article Lack of agreement between office and ambulatory blood pressure responses to hydrochlorothiazide.
Academic Article Baseline predictors of central aortic blood pressure: a PEAR substudy.
Academic Article Reproducibility of blood pressure response to hydrochlorothiazide.
Academic Article Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1/TSC2 contiguous gene syndrome.
Academic Article Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects.
Academic Article PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.
Academic Article Tolvaptan in patients with autosomal dominant polycystic kidney disease.
Academic Article Cardiac magnetic resonance assessment of left ventricular mass in autosomal dominant polycystic kidney disease.
Academic Article A multilocus approach to the antihypertensive pharmacogenetics of hydrochlorothiazide.
Academic Article WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic.
Academic Article Effects of endothelial nitric oxide synthase, alpha-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide.
Academic Article Quality of life in autosomal dominant polycystic kidney disease patients not yet on dialysis.
Academic Article Comparison of methods for determining renal function decline in early autosomal dominant polycystic kidney disease: the consortium of radiologic imaging studies of polycystic kidney disease cohort.
Academic Article Magnetic resonance measurements of renal blood flow and disease progression in autosomal dominant polycystic kidney disease.
Academic Article MRI-based kidney volume measurements in ADPKD: reliability and effect of gadolinium enhancement.
Academic Article Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study.
Academic Article Segmentation of individual renal cysts from MR images in patients with autosomal dominant polycystic kidney disease.
Academic Article Evaluation of urine biomarkers of kidney injury in polycystic kidney disease.
Academic Article Predictors for glucose change in hypertensive participants following short-term treatment with atenolol or hydrochlorothiazide.
Academic Article A Physiologic Approach to the Pharmacogenomics of Hypertension.
Academic Article Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.
Academic Article Large-scale gene-centric analysis identifies polymorphisms for resistant hypertension.
Academic Article PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment.
Academic Article TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
Academic Article Cardiac and renal effects of standard versus rigorous blood pressure control in autosomal-dominant polycystic kidney disease: results of a seven-year prospective randomized study.
Academic Article Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension.
Academic Article Volume progression in polycystic kidney disease.
Academic Article Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study.
Academic Article Association of branched and aromatic amino acids levels with metabolic syndrome and impaired fasting glucose in hypertensive patients.
Academic Article Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease.
Academic Article Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response.
Academic Article Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide.
Academic Article Predictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertension.
Academic Article Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide.
Academic Article Angiotensin blockade in late autosomal dominant polycystic kidney disease.
Academic Article A novel simple method for determining CYP2D6 gene copy number and identifying allele(s) with duplication/multiplication.
Academic Article Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
Academic Article Lack of correlation between thiazide-induced hyperglycemia and hypokalemia: subgroup analysis of results from the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.
Academic Article Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications.
Academic Article Comparison of office, ambulatory, and home blood pressure antihypertensive response to atenolol and hydrochlorthiazide.
Academic Article Liver involvement in early autosomal-dominant polycystic kidney disease.
Academic Article Magnetic resonance measurements of renal blood flow as a marker of disease severity in autosomal-dominant polycystic kidney disease.
Academic Article Mutations in GANAB, Encoding the Glucosidase IIa Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease.
Academic Article Renal volume in children with ADPKD: size matters.
Academic Article Approaches to testing new treatments in autosomal dominant polycystic kidney disease: insights from the CRISP and HALT-PKD studies.
Academic Article A comparison of ultrasound and magnetic resonance imaging shows that kidney length predicts chronic kidney disease in autosomal dominant polycystic kidney disease.
Academic Article The role of parental hypertension in the frequency and age of diagnosis of hypertension in offspring with autosomal-dominant polycystic kidney disease.
Academic Article Comparison of Blood Pressure Control Rates Among Recommended Drug Selection Strategies for Initial Therapy of Hypertension.
Academic Article Reproducibility of Genotypes as Measured by the Affymetrix GeneChip® 100K Human Mapping Array Set.
Academic Article Albuminuria and tolvaptan in autosomal-dominant polycystic kidney disease: results of the TEMPO 3:4 Trial.
Academic Article Effect of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease by CKD Stage: Results from the TEMPO 3:4 Trial.
Academic Article Volume progression in autosomal dominant polycystic kidney disease: the major factor determining clinical outcomes.
Academic Article Recurrence of intracranial aneurysms in autosomal-dominant polycystic kidney disease.
Academic Article Medical resource utilization and costs associated with autosomal dominant polycystic kidney disease in the USA: a retrospective matched cohort analysis of private insurer data.
Academic Article Treatment of autosomal dominant polycystic kidney disease (ADPKD): the new horizon for children with ADPKD.
Academic Article Automated Segmentation of Kidneys from MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease.
Academic Article Automated segmentation of liver and liver cysts from bounded abdominal MR images in patients with autosomal dominant polycystic kidney disease.
Academic Article Magnetic resonance imaging evaluation of hepatic cysts in early autosomal-dominant polycystic kidney disease: the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort.
Academic Article Autosomal dominant polycystic kidney disease: time for a change?
Academic Article Mechanisms and management of hypertension in autosomal dominant polycystic kidney disease.
Academic Article Polycystic kidney disease: The cadence of kidney growth in ADPKD.
Academic Article The HALT polycystic kidney disease trials: design and implementation.
Academic Article Gastrointestinal Manifestations of Autosomal-Dominant Polycystic Kidney Disease.
Academic Article Prognostic enrichment design in clinical trials for autosomal dominant polycystic kidney disease: the HALT-PKD clinical trial.
Academic Article Urine Osmolality, Response to Tolvaptan, and Outcome in Autosomal Dominant Polycystic Kidney Disease: Results from the TEMPO 3:4 Trial.
Academic Article Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.
Academic Article Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol.
Academic Article Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.
Academic Article Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Academic Article Image texture features predict renal function decline in patients with autosomal dominant polycystic kidney disease.
Academic Article Fibroblast Growth Factor 23 and Kidney Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
Academic Article New treatment paradigms for ADPKD: moving towards precision medicine.
Academic Article A Patient with a Novel Gene Mutation Leading to Autosomal Dominant Polycystic Kidney Disease.
Academic Article Hypoxia-Inducible Factor 1a (HIF-1a), Angiopoietin-2 (ANG-2) and Endocan: Novel Biomarkers of Disease Progression Involving Polycystic Kidney Disease.
Academic Article Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.
Academic Article Nurturing passion in a time of academic climate change: the modern-day challenge of junior faculty development.
Academic Article Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.
Academic Article Standardised Outcomes in Nephrology-Polycystic Kidney Disease (SONG-PKD): study protocol for establishing a core outcome set in polycystic kidney disease.
Academic Article Effect of Statin Therapy on the Progression of Autosomal Dominant Polycystic Kidney Disease. A Secondary Analysis of the HALT PKD Trials.
Academic Article Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses).
Academic Article Tolerability of Aquaretic-Related Symptoms Following Tolvaptan for Autosomal Dominant Polycystic Kidney Disease: Results From TEMPO 3:4.
Academic Article Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension.
Academic Article Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.
Academic Article Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/ß-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.
Academic Article Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease.
Academic Article Multicenter, open-label, extension trial to evaluate the long-term efficacy and safety of early versus delayed treatment with tolvaptan in autosomal dominant polycystic kidney disease: the TEMPO 4:4 Trial.
Academic Article Determinants of Progression in Early Autosomal Dominant Polycystic Kidney Disease: Is it Blood Pressure or Renin-Angiotensin-Aldosterone-System Blockade?
Academic Article A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan.
Academic Article Autosomal dominant polycystic kidney disease.
Academic Article Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide.
Academic Article Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy.
Academic Article Relationship between caffeine intake and autosomal dominant polycystic kidney disease progression: a retrospective analysis using the CRISP cohort.
Academic Article Identifying patient-important outcomes in polycystic kidney disease: An international nominal group technique study.
Academic Article Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension.
Academic Article Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies.
Academic Article The future of pharmacogenetics in the treatment of hypertension.
Academic Article Plasma copeptin levels predict disease progression and tolvaptan efficacy in autosomal dominant polycystic kidney disease.
Academic Article Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease.
Academic Article Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta-Blockers in European Americans.
Academic Article Growth Pattern of Kidney Cyst Number and Volume in Autosomal Dominant Polycystic Kidney Disease.
Academic Article ß2 -Adrenergic Receptor Gene Affects the Heart Rate Response of ß-Blockers: Evidence From 3 Clinical Studies.
Academic Article Genome-Wide Meta-Analysis of Blood Pressure Response to ß1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).
Academic Article Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.
Academic Article Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response.
Academic Article Erythropoietin and Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease Patients.
Academic Article A Practical Approach to Polycystic Liver Disease.
Academic Article Expanded Imaging Classification of Autosomal Dominant Polycystic Kidney Disease.
Academic Article The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD.
Academic Article Advancing Nephrology: Division Leaders Advise ASN.
Academic Article 'A sword of Damocles': patient and caregiver beliefs, attitudes and perspectives on presymptomatic testing for autosomal dominant polycystic kidney disease: a focus group study.
Academic Article Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.
Academic Article Multicenter Study of Long-Term Safety of Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease.
Academic Article Race-Specific Comparisons of Antihypertensive and Metabolic Effects of Hydrochlorothiazide and Chlorthalidone.
Academic Article Sex Differences of Kidney Stone Urine Risk Factors after Roux-en-Y Gastric Bypass.
Academic Article The Effect of Tolvaptan on BP in Polycystic Kidney Disease: A Post Hoc Analysis of the TEMPO 3:4 Trial.
Academic Article Patient-reported outcome measures for pain in autosomal dominant polycystic kidney disease: A systematic review.
Academic Article Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients.
Academic Article PKD1 Compared With PKD2 Genotype and Cardiac Hospitalizations in the Halt Progression of Polycystic Kidney Disease Studies.
Academic Article Establishing a core outcome measure for pain in patients with autosomal dominant polycystic kidney disease: a consensus workshop report.
Academic Article Volume Progression and Imaging Classification of Polycystic Liver in Early Autosomal Dominant Polycystic Kidney Disease.
Academic Article Emerging Role of Clinical Genetics in CKD.
Academic Article Polycystic Kidney Disease in the Real World.
Academic Article Controversies in renal artery stenosis: a review by the American Society of Nephrology Advisory Group on Hypertension.
Academic Article Chronic Kidney Disease Classification in Systolic Blood Pressure Intervention Trial: Comparison Using Modification of Diet in Renal Disease and CKD-Epidemiology Collaboration Definitions.
Academic Article Study Design and Baseline Characteristics of the CARDINAL Trial: A Phase 3 Study of Bardoxolone Methyl in Patients with Alport Syndrome.
Academic Article Health Disparities in Autosomal Dominant Polycystic Kidney Disease (ADPKD) in the United States.
Academic Article Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients.
Academic Article Effects of Bardoxolone Methyl in Alport Syndrome.
Academic Article The STAGED-PKD 2-Stage Adaptive Study With a Patient Enrichment Strategy and Treatment Effect Modeling for Improved Study Design Efficiency in Patients With ADPKD.
Academic Article Utility of new image-derived biomarkers for autosomal dominant polycystic kidney disease prognosis using automated instance cyst segmentation.
Concept Lipocalin-2
Concept Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Concept Circulating MicroRNA
Concept Essential Hypertension
Concept Nedd4 Ubiquitin Protein Ligases
Concept Bestrophins
Concept Apolipoprotein L1
Concept Antidiuretic Hormone Receptor Antagonists
Grant Symposium for Molecular and Therapeutic Insights in PKD
Grant Limited Competition: Clinical Centers for the HALT-Polycystic Kidney Disease Tria
Academic Article Intracranial Aneurysms in ADPKD: How Far Have We Come?
Academic Article OVERTURE: A Worldwide, Prospective, Observational Study of Disease Characteristics in Patients With ADPKD.
Academic Article Magnetic resonance imaging preprocessing and radiomic features for classification of autosomal dominant polycystic kidney disease genotype.
Academic Article Circulating microRNA Biomarkers of Thiazide Response in Hypertension.
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